The 1st International Post-Tuberculosis Symposium.
Life after TB.
STIAS Institute, Stellenbosch, South Africa
22-23 July 2019
The Symposium
Two Days of Powerful Talks and Workshops
BACKGROUND
AIMS & OBJECTIVES
1. To advocate for patients suffering with post-TB complications.
2. To facilitate face-to-face networking between leaders in the field.
3. To define the current state of knowledge surrounding post-TB disease, in a number of important areas
4. To discuss and achieve consensus on important aspects of post-TB lung diseases
5. To produce a reference document for researchers and workers in the field
The World Health Organisation (WHO) estimates that approximately 54 million people survived TB between 2000 and 2017 alone. There is increasing evidence of long term respiratory complications following TB in a proportion of these patients, preventing them from returning to their normal lives. Patients can suffer from airflow obstruction, restrictive and fibrotic defects, bronchiectasis and aspergillomas amongst other conditions. With chronic obstructive pulmonary disease (COPD) being the third leading cause of death worldwide, the problem of post-TB chronic respiratory disorders could be substantial. In addition to the physiological and anatomical consequences, people who have survived TB often suffer significant economic and psychological consequences, which the international literature is starting to recognise. Despite emerging evidence, there is still a lack of international guidelines and recommendations on the follow up of patients beyond the cure of TB. While WHO’s Global Action Plan on non-communicable diseases recommends incorporating screening for chronic respiratory disease in TB clinics, the WHO End TB Strategy neglects post-TB respiratory disorders.
Proceedings Report
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The Global Steering Committee
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Brian Allwood, Stellenbosch University (Chair)
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Sumona Datta, Imperial College London and the University of Lima (in absentia)
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Carlton Evans, Imperial College London and the University of Lima (in absentia)
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Olena Ivanova, Tropical Institute Munich
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Rupert Jones, the University of Plymouth (in absentia)
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Florian Marx, Stellenbosch University
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Jamilah Meghji, Liverpool School of Tropical Medicine
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Kevin Mortimer, Liverpool School of Tropical Medicine
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Stellah Mpagama, Kibong’oto Infectious Diseases Hospital
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Andrea Rachow, Tropical Institute Munich
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Marieke van der Zalm, Stellenbosch University
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Sanne van Kampen, University of Plymouth
Participants
67
Workshops
8
Sessions
6
Speakers
14
Programme
Day 1: 22/07/2019
Session 1: Chair Brian Allwood & Kevin Mortimer
8.30 - 09.00
Welcome, Introductions and Expectations (Brian Allwood / Kevin Mortimer)
09.00 - 09.10
Message from Rector of Stellenbosch University (Wim de Villiers)
09.10 - 09.30
Opening Address (Eric Bateman)
09.30 - 09.50
Lecture #1: Patient perspectives (Ingrid Schoeman)
09.50 - 10.10
Lecture #2: Pulmonary TB outcomes (Andrea Rachow)
10.10 - 10.30
Lecture #3: Phenotyping in post-TB disease (Brian Allwood)
10.30 - 11.00
TEA
Session 2: Chair Jamilah Meghji & Stellah Mpagama
11.00 - 11.20
Lecture #4: Children after TB (Diane Gray)
11.20 - 11.40
Lecture #5: Socio-economic consequences & QALY (Denise Evans)
11.40 - 12.00
Lecture #6: Targeting TB control to former TB patients (Florian Marx)
12.00 - 13.00
GROUP PHOTOGRAPH & LUNCH
Workshops
13.00 - 15.00
Workshop 1: Lung complications after TB
(Brian Allwood / Jamilah Meghji)
Workshop 2: Former TB patients in the context of the End TB Strategy
(Florian Marx / Dalene von Delft / Sumona Datta)
Workshop 3: Socio-economic and psychological Impact
(Olena Ivanova / Denise Evans / Graeme Hoddinott)
Workshop 4: Paediatric complications of TB
(Marieke van der Zalm / Diane Gray)
15.00 - 15.30
TEA
15.30 - 16.30
Workshops 1-4 (continue)
16:30 - 17.30
Plenary Workshop Feedback
17.30
Dinner for all delegates
Day 2: 23/07/2019
Session 3: Chair Sanne van Kampen & Florian Marx
08.30 - 08.40
Logistics Update
08.40 - 09.00
Lecture #7: Mechanisms of TB destruction (Naomi Walker)
09.00 - 09.20
Lecture #8: Host directed therapy to improve TB outcomes (Rob Wallis)
09.20 - 09.40
Lecture #9: Pulmonary rehabilitation (William Worodria)
09.40 - 10.00
Lecture #10: Therapies for treatment post TB (Stellah van Kampen)
10.00 - 10.20
Lecture #11: Malawian cohort (Jamilah Meghji)
10.20 - 11.00
TEA
Session 4: Chair Marieke van der Zalm & Andrea Rachow
11.00 - 11.20
Lecture #12: Advocacy for Post-TB disease (Kevin Mortimer)
11.20 - 11.40
Lecture #13: Diagnosing recurrent TB among former TB patients (Grant Theron)
11.40 - 12.00
Lecture #14: Mortality after TB (Mohammed Osman)
12.00 - 13.00
LUNCH
Workshops
13.00 - 15.00
Workshop 5: Pathogenesis /mechanisms of disease & prevention of damage
(Naomi Walker / Cari Stek / Rob Wallis)
Workshop 6: Treatment & holistic management
(Sanne van Kampen / (Rupert Jones) / Stellah Mpagama)
Workshop 7: Health systems advocacy
(Kevin Mortimer / Uzoh Egere / Ingrid Schoeman)
Workshop 8: Burden of disease/risk factors/mortality (Epidemiology)
Andrea Rachow / Andre Amaral
15.00 - 15.30
TEA
15.30 - 16.30
Workshops 1 - 4 (continue)
16.30 - 17.30
Plenary Workshop Feedback
17.30 - 18.00
Discussion: Focus of Definitions
18.00
DINNER FOR STEERING COMMITTEE & WORKSHOP CHAIRS
Sponsors
Meet The Delegates
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Things To Do
Wine farms:
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Rust en Vrede Wine Estate
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Jordan Wine Estate
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De Meye Wine Farm
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Lanzerac Wine Estate
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Hidden Valley Wines
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Delaire Graff
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Kleine Zalze Wine Estate
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Stark-Conde Wines
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Tokara Wine Estate
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Simonsig
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The Fat Butcher
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Stellenbosch Kitchen
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Asta La Pasta Restaurant
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De Vrije Burger
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Meraki
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Oppie Dorp Restaurant
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Spek en Bone